NEW YORK, October 25, 2022 — Voltron Therapeutics, a Lucius Partners portfolio company, announced the company’s poster on its proprietary Self-Assembling Vaccine platform was selected for presentation and discussed at the Military Health System Research Symposium (MHSRS).
The MHSRS is the Department of Defense’s largest scientific meeting and is designed to highlight new scientific approaches to address DoD research priorities. Military leaders, academic researchers, and industry present and collaborate on research / health care initiatives falling under numerous topic areas including Military Infectious Diseases.
The presentation provided data indicating that the VaxCelerate platform technology could offer potential therapeutic and preventive options to address specific military needs, as well as the needs of the general population.
Dr. Mark Poznansky, Director of the Vaccine and Immunotherapy Center, along with Dr. Jeff Gelfand at Massachusetts General Hospital stated, “We are extremely pleased to be selected to present the foundational data in support of the Self-Assembling Vaccine platform. This initial academic work was supported by a grant from the DoD and was published in peer reviewed Human Vaccines and Immunotherapies. We established the VaxCelerate technology at VIC and MGH to address the need for rapid vaccine development by creating a platform capable of generating and pre-clinically testing a new vaccine against specific pathogen targets in less than 120 days. Our subsequent pre-clinical work continues to support a safe vaccine approach that comes along with rapid development capabilities, the ability to induce a broad immune response to a pathogen, and potentially maximal flexibility/ability to respond to viral variants of concern.”
POSTER: VaxCelerate: the Use of MTBhsp70-Avidin as an Adjuvant to Create Self-Assembling Vaccines for Emerging Infectious Diseases Vaccine and Immunotherapy Center, MGH and Voltron Therapeutics Inc.
SESSION: Medical Readiness
SECTION: Development of New Front Line Therapies to Prevent and Treat Endemic Viral Diseases (non-SARS CoV2)
This poster concluded that Voltron’s self-assembled vaccines appear to augment cell-mediated immune responses to immunogenic peptides OVA, Flu and Lassa Fever, with the fusion protein between Mycobacterium tuberculosis heath shock protein 70 and the protein Avidin (referred as MTBhsp70-Avidin) acting as safe and efficacious broad immune activating adjuvant in this context for T cell mediated responses to pathogens.
Patrick Gallagher, CEO of Voltron Therapeutics stated “Voltron is grateful to have had the opportunity to discuss the VaxCelerate platform’s attributes, such as easy distribution/deployment logistics relative to a number of other vaccines, and potential applicability to meeting specific military needs with a variety of DoD constituents at MHSRS. We continue to demonstrate that the self-assembled vaccine structure triggers significant cell-mediated immune responses against different pathogens by altering the immunogenic targeting peptide in different animal models and disease states in infectious disease and cancer.
“We are pleased to continue to introduce our portfolio companies and their technologies to a wide variety of potentially relevant public, private, strategic and financial stakeholder groups,” said James Ahern, Founding Partner of Lucius Partners. “MHSRS provided an excellent opportunity to expand awareness of Voltron’s unique capabilities.”
About Voltron Therapeutics, Inc.
Voltron Therapeutics, Inc., a Delaware corporation, was founded in 2017 to lead and accelerate the development of the Vaccine and Immunotherapy Center (VIC), and the Massachusetts General Hospital’s novel Self Assembling Vaccine technology in a variety of indications, including in Oncology and Emerging Infectious Diseases. Voltron holds an exclusive worldwide license to this technology. With the work of our world class team of researchers and development team, this technology has shown in certain pre-clinical studies initial proof of concept in two infectious diseases (including Lassa Fever) as well as two oncology indications (Ovarian and HPV Related Cancers). For more information, please visit www.voltrontx.com.
About Lucius Partners, LLC
Lucius Partners is a consultancy that provides a broad suite of services to help healthcare companies grow, achieve milestones and generate value for their shareholders.
Forward Looking Statements
This press release includes “forward-looking statements” within the meaning of the Private Securities Litigation Reform Act of 1995. Forward-looking statements in this press release include, but are not limited to, statements that relate to the advancement and development of the Self-Assembling Vaccine Platform, the commencement of clinical trials, the availability of data from clinical trials and other information that is not historical information. When used herein, words such as “anticipate”, “being”, “will”, “plan”, “may”, “continue”, and similar expressions are intended to identify forward-looking statements. In addition, any statements or information that refer to expectations, beliefs, plans, projections, objectives, performance or other characterizations of future events or circumstances, including any underlying assumptions, are forward-looking. All forward-looking statements are based upon Voltron’s current expectations and various assumptions. Voltron believes there is a reasonable basis for its expectations and beliefs, but they are inherently uncertain. Voltron may not realize its expectations, and its beliefs may not prove correct. Actual results could differ materially from those described or implied by such forward-looking statements as a result of various important factors, including, without limitation, market conditions and any Voltron filings made with the Securities and Exchange Commission. Consequently, forward-looking statements should be regarded solely as Voltron’s current plans, estimates and beliefs. Investors should not place undue reliance on forward-looking statements. Voltron cannot guarantee future results, events, levels of activity, performance or achievements. Voltron does not undertake and specifically declines any obligation to update, republish, or revise any forward-looking statements to reflect new information, future events or circumstances or to reflect the occurrences of unanticipated events, except as may be required by law.
Patrick Gallagher, CEO
Voltron Therapeutics, Inc.
Lucius Partners, LLC
Matthew Duffy, President
Voltron Therapeutics, Inc.
Lucius Partners, LLC